Severe acute bronchiolitis in children: etiology, therapy, effectiveness of 3% hypertonic saline containing sodium hyaluronate

Introduction . Acute bronchiolitis (АB) is a common infection in children under the age of 2 years. In modern clinical protocols, routine use studied drugs not recommended. The effectiveness 3% hypertonic sodium chloride solution (HSCS) at vol. А im Тo study etiology, risk factors, therapy acute care intensive units (ICU), inhalations with HSCS hyaluronate (HS) comparison without inclusion this drug. Materials and methods medical documentation 54 patients AB from January 2021 to 2023 who were treated ICU was analyzed. An ambispective comparative HS conducted historical control. Results Respiratory syncytial viral (RSV) etiology established 50% patients. most factor for disease younger than 3 months (40.7%). presence factors severe course respiratory failure had an impact on average bed-day need support (p = 0.04), addition which often received drug therapy. There no statistically significant differences terms hospitalization, duration depending appointment > 0.05), however, there improvement functional dynamics estimated by modified scale Wood’s asthma 2nd day disease. Conclusion has RSV developing course. influence guidelines treatment remains controversial. can improve flow AB.